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Many patients have safely reduced steroid or extra DMARD and biologic use

FIGURE 3 3.3 Neuroprotective activity Alzheimers disease (AD) is pathologically defined by the accumulation of amyloid-beta (A) plaques and hyperphosphorylated Tau proteins, disrupting the autophagy-lysosomal pathway (ALP) and causing neuronal death (Table 1, Row 18)

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